Internet Explorer won't stop making click noises!
The biggest annoyance with asynchronous postbacks through an iframe is probably the infamous "click" noises that Internet Explorer makes when you load a page. I've turned sounds for that event off (in the sounds section of the control panel) a long time ago, and it's easy to forget about it once it's gone.
It turns out that we're not the only ones that have this clicking going on. The Yahoo! Mail Beta Team blogged about it too, check it out: http://updates.mail.yahoo.com/blog/archives/27
