What do you mean by "pre-defined parameters"? If you are talking about profile settings that can be selected from a list in the driver interface, TWAIN does not have anyway to access those. If you are simply talking about the user changing settings and then saving those settings to file so you can load them later, using the Load and Save methods will work fine.
To me it sounds like you are trying to manually modify the XML file after saving it in order to change the settings later. This is not a good idea since each scanner is different and support different capabilities. What you might want to do is just have a list of general settings that the user can save, then when they want to scan with a specific setup you would set the properties just before you call Acquire.
Glenn Chittenden Jr.
Atalasoft Development Team